Jeffersonville is a village in Wayne County, Illinois, United States. The population was 366 at the 2000 census.
Jeffersonville is located at 38°26′31″N 88°24′16″W / 38.44194°N 88.40444°W / 38.44194; -88.40444 (38.442024, -88.404562).
According to the 2010 census, Jeffersonville has a total area of 1.02 square miles (2.64 km), all land.
As of the census of 2000, there were 366 people, 156 households, and 99 families residing in the village. The population density was 358.8 people per square mile (138.5/km²). There were 171 housing units at an average density of 167.6 per square mile (64.7/km²). The racial makeup of the village was 97.81% White, 1.37% African American, 0.55% Native American, 0.27% from other races. Hispanic or Latino of any race were 2.46% of the population.
There were 156 households out of which 34.6% had children under the age of 18 living with them, 50.0% were married couples living together, 12.2% had a female householder with no husband present, and 36.5% were non-families. 32.1% of all households were made up of individuals and 16.7% had someone living alone who was 65 years of age or older. The average household size was 2.35 and the average family size was 2.98.
In the village, the population was spread out with 28.1% under the age of 18, 9.0% from 18 to 24, 26.2% from 25 to 44, 18.6% from 45 to 64, and 18.0% who were 65 years of age or older. The median age was 34 years. For every 100 females, there were 98.9 males. For every 100 females age 18 and over, there were 82.6 males.
The median income for a household in the village was $25,521, and the median income for a family was $28,500. Males had a median income of $25,521 versus $16,458 for females. The per capita income for the village was $11,882. About 15.4% of families and 19.7% of the population were below the poverty line, including 23.7% of those under age 18 and 21.1% of those age 65 or over.