Brussels is a village in Calhoun County, Illinois, United States. The population was 141 at the 2010 census, that figure representing no change from its 2000 population.
Brussels is located at 38°56′50″N 90°35′19″W / 38.94722°N 90.58861°W / 38.94722; -90.58861 (38.947275, -90.588630).
According to the 2010 census, Brussels has a total area of 0.56 square miles (1.45 km), all land.
As of the census of 2000, there were 141 people, 60 households, and 40 families residing in the village. The population density was 232.4 people per square mile (89.2/km²). There were 70 housing units at an average density of 115.4 per square mile (44.3/km²). The racial makeup of the village was 100.00% White. Hispanic or Latino of any race were 2.84% of the population.
There were 60 households out of which 30.0% had children under the age of 18 living with them, 51.7% are married couples living together, 8.3% had a female householder with no husband present, and 33.3% were non-families. 28.3% of all households were made up of individuals and 13.3% had someone living alone who was 65 years of age or older. The average household size is 2.35 and the average family size was 2.80.
In the village, the population was spread out with 20.6% under the age of 18, 11.3% from 18 to 24, 27.7% from 25 to 44, 20.6% from 45 to 64, and 19.9% who are 65 years of age or older. The median age is 39 years. For every 100 females, there were 104.3 males. For every 100 females age 18 and over, there were 89.8 males.
The median income for a household in the village was $40,938, and the median income for a family was $46,250. Males had a median income of $29,375 versus $15,417 for females. The per capita income for the village was $16,281. 11.4% of the population and 5.7% of families are below the poverty line. Out of the total population, none of those under the age of 18, but 17.4% of those 65 and older, were living below the poverty line.